Hjerte-karsygdom og kosttilskud - videnskabelige referencer

  1. Anderson TW et al. A double-blind trial of vitamin E in angina pectoris. Am J Clin Nutr 27:1174-8, 1974.
  2. Azen SP, Qian D, Mack W, et al. Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering. Circulation 94;10:2369-72, 1996.
  3. Barboriak JJ et al. Vitamin E supplements and plasma high-density lipoprotein cholesterol. Letter. Am J Clin Pathol 77;3:371, 1982.
  4. Bellizzi MC, Franklin MF, Duthie GG, et al. Vitamin E and coronary heart disease: the European paradox. Eur J Clin Nutr 48:822-31, 1994.
  5. Bierenbaum M, Reichstein R, Bhagavan H, et al. Relationship between serum lipid peroxidation products in hypercholesterolemic subjects and vitamin E status. Biochem Int 28:57-66, 1992.
  6. Boers GH. Hyperhomocysteinaemia: a newly recognized risk factor for vascular disease. Neth J Med 45:1:34-41, 1994.
  7. Boniton-Kopp C, Coudray C, Berr C, et al. Combined effects of lipid peroxidation and antioxidant status on carotid atherosclerosis in a population aged 59-71 y: The Eva study.Am J Clin Nutr 65:121-7, 1997.
  8. Bordia A et al. Effect of vitamin C on platelet adhesiveness and platelet aggregation in coronary artery disease patients. Clin Cardiol 810:552-4, 1985.
  9. Brattström L et al. Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment. Atherosclerosis 81:1:51-60, 1990.
  10. Brattström L, Stavenow L, Galvard H, et al. Pyridoxine reduces cholesterol and low-density-lipoprotein and increases antithrombin III activity in 80- year-old men with low plasma pyridoxal 5-phosphate. Scand J Clin Lab Invest 50:8:873-7, 1990.
  11. Brattström L. Vitamins as homocysteine-lowering agents: a mini review. Presentation at the American Institute of Nutrition Colloquium, April 13, 1995, Atlanta, Georgia; Brattström L. Vitamins as homocysteine-lowering agents. J Nutr 126:4 Suppl:1276S-1280S, 1996.
  12. Calzada C, Bruckdorfer K, Rice-Evans C. The influence of antioxidant nutrients on platelet function in healthy volunteers. Atherosclerosis 128;1:97-105, 1997.
  13. Campos AM, Lissi EA, Total antioxidant potential of Chilean wines. Nutr Res 16:385-9, 1996.
  14. Carpenter KLH, Cheeseman KH, Van Der Veen C, et al. Depletion of alpha-tocopherol in human atherosclerotic lesions. Free Rad Res 23:549- 58, 1995.
  15. Cavarocchi NC et al. Superoxide generation during cardiopulmonary bypass: Is there a role for vitamin E? J Surg Res 40:519-27, 1986.
  16. Chakrabarty S, Nandi A, Mukhopadhyay C, et al. Protective role of ascorbic acid against lipid peroxidation and myocardial injury. Mol Cell Biochem 111:41-7, 1992.
  17. Chamiec T et al. Effects of antioxidant vitamins C and E on signal-averaged electro-cardiogram and acute myocardial infarction. Am J Cardiol 77:237-41, 1996.
  18. Choi ESK et al. Correlation of plasma ascorbic acid with cardiovascular risk factors. Am J Clin Nutr 51:511, 1990.
  19. Cloarec MJ et al. Alpha-tocopherol: Effect on plasma lipoproteins in hypercholesterolemic patients. Isr J Med Sci 23;8:869-72, 1987.
  20. Coghlan JG, Flitter WD, Clutton SM, et al. Lipid peroxidation and changes in vitamin E levels during coronary artery bypass grafting. J Thorac Cardiovasc Surg 106;2:268-74, 1993.
  21. Creter D et al. Effect of vitamin E on platelet aggregation in diabetic retinopathy. Acta Hematol 62:74, 1979.
  22. Dalery K et al. Homocysteine and coronary artery disease in French Canadian subjects: relation with vitamins B12, B6, pyridoxal phosphate and folate. Am J Cardiol 75:1107-11, 1995.
  23. Dallal GE et al. Ascorbic acid, HDL cholesterol, and apolipoprotein A-I in an elderly Chinese population in Boston. J Am Coll Nutr 8;1:69-74, 1989.
  24. De Lorgeril , Boissonnat P, Salen P, et al. The beneficial effect of dietary antioxidant supplementation on platelet aggregation and cyclosporine treatment in heart transplant recipients. Transplantation 58:193-4, 1994.
  25. DeMaio SJ et al. Vitamin E supplementation, plasma lipids and incidence of restenosis after percutaneous transluminal coronary angioplasty PTCA. J Am Coll Nutr 11;1:68-73, 1992.
  26. Dieber-Rotheneder M et al. Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation. J Lipid Res 32:1325- 32, 1991.
  27. Dobson HM et al. The effect of ascorbic acid on the seasonal variations in serum cholesterol levels. Scot Med J 293:176-82, 1984.
  28. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology 3:3:194-202, 1992.
  29. Eriksson J, Kohvakka A. Magnesium and ascorbic acid supplementation in diabetes mellitus. Ann Nutr Metab 394:217-23, 1995.
  30. Esk C et al. Correlation of plasma ascorbic acid with cardiovascular risk factors. Clin Res 38:A747, 1990.
  31. Ferreira R et al. Antioxidant action of vitamins A and E in patients submitted to coronary bypass surgery. Vasc Surg 25:191-5, 1991.
  32. Gartside PS, Glueck CJ. Relationship of dietary intake to hospital admission for coronary heart and vascular disease: The NHANES II National Probability Study. J Am Coll Nutr 12:6:5676-84, 1993.
  33. Gatto LM, Hallen GK, Brown AJ, Samman S. Ascorbic acid induces a favorable lipoprotein profile in women. J Am Coll Nutr 152:154-8, 1996.
  34. Gey KF et al. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. Am J Clin Nutr 53:326S-34S, 1991.
  35. Gey KF, Stahelin HB, Eichholzer M. Poor plasma status of carotene and vitamin C is associated with higher mortality from ischemic heart disease and stroke: Basel Prospective Study. Clin Invest 71:3-6, 1993.
  36. Ginter E et al. Vitamin C in the control of hypercholesterolemia in man. Int J Vitam Nutr Res Suppl 23:137-52, 1982; Turley S et al. Role of ascorbic acid in the regulation of cholesterol metabolism and the pathogenesis of atherosclerosis. Atherosclerosis 24:1-18, 1976.
  37. Ghosh S, et al. Dietary intake and plasma levels of antioxidant vitamins in health and disease: a hospital-based case-control study. J Nutr Environ Med 5:235-42, 1995.
  38. Gribauskas P et al. [Manganese levels in hair as an additional indicator for early diagnosis of ischemic disease of the heart.] Lab Delo ;10:629, 1985.
  39. Hallfrisch J et al. High plasma vitamin C associated with increased plasma HDL- and HDL 2 -cholesterol. Clin Res 39:A203, 1991.
  40. Hallfrisch J, Singh VN, Muller DC, et al. High plasma vitamin C associated with high plasma HDL-and HDL2 cholesterol. Am J Clin Nutr 60:100-5, 1994.
  41. Hennig B et al. Protective effects of vitamin E in age-related endothelial cell injury. Int J Vitam Nutr Res 59:273-9, 1989.
  42. Hennig B. Mechanisms of atherosclerosis: Nutrition and endothelial cell integrity. Abstract. J Am Coll Nutr 12:594, 1993.
  43. Herbaczynska-Cedro K, Klosiewicz-Wasek B, Cedro K, et al. Supplementation with vitamins C and E suppresses leukocyte oxygen free radical production in patients with myocardial infarction. Eur Heart J 16:1044-9, 1995.
  44. Hermann WJ et al. The effect of tocopherol on high-density lipoprotein cholesterol: A clinical observation. Am J Clin Pathol 72:848-52, 1979.
  45. Hodis HN, Mack WJ, LaBree L, et al. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis. JAMA 273;23:1849-54, 1995.
  46. Horsey J, Livesley B, Dickerson JW. Ischemic heart disease and aged patients: effects of ascorbic acid on lipoproteins. J Hum Nutr 35:1:53-8, 1981.
  47. Jacques PF et al. Ascorbic acid, HDL, and total plasma cholesterol in the elderly. J Am Coll Nutr 6;2:169-74, 1987.
  48. Jacques PF. Effects of vitamin C on high-density lipoprotein cholesterol and blood pressure. J Am Coll Nutr 11;2:139-44, 1992.
  49. Jacques PF, Sulsky SI, Perrone GA, Schaefer EJ. Ascorbic acid and plasma lipids. Epidemiology 5:19-24, 1994.
  50. Jacques PF, Sulsky SI, Perrone GE, et al. Effect of vitamin C supplementation on lipoprotein cholesterol, apolipoprotein, and triglyceride concentrations. Ann Epidemiol 51:52-9, 1995.
  51. Jain SK, McVie R, Jaramillo JJ, et al. The effect of modest vitamin E supplementation on lipid peroxidation products and other cardiovascular risk factors in diabetic patients. Lipids 31:S87-90, 1996.
  52. Jandak J et al. Reduction of platelet adhesiveness by vitamin E supplementation in humans. Thrombosis Res 49:393-404, 1988.
  53. Jandak J et al. Alpha tocopherol, an effective inhibitor of platelet adhesion. Blood 73:141-9, 1989.
  54. Jenkins David JA et al. Effect of a diet high in vegetables, fruit, and nuts on serum lipids. Metabolism 46:5:530-37, 1997.
  55. Jenkens DJ. Optimal diet for reducing the risk of arteriosclerosis. Can J Cardiol 11Suppl G:118G-121G, 1995.
  56. Jialal I, Vega Gl, Grundy SM. Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein. Atherosclerosis 82:185-91, 1990.
  57. Jialal I, Grundy SM. Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein. J Lipid Res 33;6:899-906, 1992.
  58. Jialal L, Fuller CJ, Hunt BA. The effect of alpha-tocopherol supplementation on LDL oxidation. Arterioscler Thromb Vasc Biol 15:190-8, 1995.
  59. Kang SS. Treatment of hyperhomocysteeinemia: physiological basis. J Nutr 126:4 Suppl:1273S-5S, 1996.
  60. Key TJA et al. Dietary habits and mortality in 11,000 vegetarians and health conscious people: Results of a 17 year follow up. BMJ 313:775-9, 1996.
  61. Khaw K-T, Woodhouse P. Interrelation of vitamin C, infection, hemostatic factors and cardiovascular disease. BMJ 310:1559-63, 1995.
  62. Knekt P, Reunanen A, Jarvinen R, et al. Antioxidant vitamin intake and coronary mortality in an longitudinal population study. Am JEpidemiol 139:1180-9, 1994.
  63. Kok FJ et al. Low vitamin B6 status in patients with acute myocardial infarction. Am J Cardiol 63:513-16, 1989.
  64. Kok FJ et al. Decreased selenium levels in acute myocardial infarction. JAMA 261;8:1161-4, 1989.
  65. Kornecki E, Feinberg H. Mechanism of inhibition of thrombin-induced platelet aggregation by pyridoxal phosphate. Biochem Biophys Res Commun 90:3:963-8, 1979.
  66. Korpela H et al. Effect of selenium supplementation after acute myocardial infarction. Res Commun Chem Pathol Pharmacol 65:249-52, 1989.
  67. Kritchevsky SB, Shimakawa T, Tell GS, et al. Dietary antioxidants and carotid artery wall thickness: the ARIC study. Circulation 92:8:2142-50, 1995.
  68. Kunisaki M, Umeda P, Inoguchi T, et al. Vitamin E binds to specific binding sites and enhances prostacyclin production by cultured aortic endothelial cells. Thromb Haemost 68:744-51, 1992.
  69. Kushi KH, olsom AR, Prineas RJ, et al. Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women. N Engl J Med 334:1156-62, 1996.
  70. Kuzuya F. Arteriosclerosis in pyridoxine deficient-monkeys. Primates 2:99, 1959.
  71. Kuzuya F F. Experiment on arteriosclerosis and arteriolosclerosis induced in pyridoxine-deficient monkeys and their recovery. Primates 3:77, 1962.
  72. Kuzuya F. Reversibility of arteriosclerosis in pyridoxine-deficient monkeys, in G Schettler, Y Goto, Y Hata, G Klose, Eds. Atherosclerosis IV. Berlin, Springer-Verlag, 1977:275-8.
  73. Kuzuya F. Vitamin B6 and arteriosclerosis. Nagoya J Med Sci 55:1-4:1-9, 1993.
  74. Lam SC et al. Investigation of possible mechanisms of pyridoxal-5-phosphate inhibition of platelet reactions. Thrombosis Res 20:633-45, 1980.
  75. Lefavi R. Lipid-lowering effects of a dietary nicotinic acid-chromium III complex in male athletes. FASEB J 5;6:A1645, 1991.
  76. Lefavi R et al. Lipid-lowering effect of a dietary chromium III-nicotinic acid complex in male athletes. Nutr Res 13:239-49, 1993.
  77. Levene CI, Murray JC. The aetiological role of maternal B6 deficiency in the development of atherosclerosis. Lancet i:628, 1977.
  78. Levine GN, Frei B, Koulouris SN, et al. Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 93:6:1107-13, 1996.
  79. Losonczy KG, Harris TB, Havlik RJ. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly. Am J Clin Nutr 64:190-6, 1996.
  80. Lynch S, Klevay L. Effects of a dietary copper deficiency on plasma coagulation factor activities in male and female mice. J Nutr Biochem 3:387, 1992.
  81. Mancini M et al. Antioxidants in the Mediterranean diet. Can J Cardiol 11Suppl G:105-9, 1995.
  82. Manson JE, Stampfer MJ, Willett WC, et al. A prospective study of antioxidant vitamins and incidence of coronary heart disease in women. Abstract. J Am Coll Nutr 11:5:633, 1992.
  83. McCully KS, Wilson RB. Homocysteine theory of arteriosclerosis. Atherosclerosis 22:2:215-27, 1975.
  84. Meleady RA et al. Genes, greens, and homocysteine. Heart 76:103-4, 1996.
  85. Mezzetti A, Lapenna D, Pierdomenico SD, et al. Vitamins E, C and lipid peroxidation in plasma and arterial tissue of smokers and nonsmokers. Atherosclerosis 112:91-9, 1995.
  86. Miwa K, Miyagi Y, Igawa A, et al. Vitamin E deficiency in variant angina. Circulation 94;1:14-18, 1996.
  87. Moore JA et al. Selenium concentrations in plasma of patients with arteriographically defined coronary atherosclerosis. Clin Chem 30:1171, 1984.
  88. Muckle T, Hazir D. Variation in human blood high-density lipoprotein response to oral vitamin E megadosage. Am J Clin Pathol 91:165-71, 1989.
  89. Mudd SH et al. The natural history of homocystinuria due to cystathionine beta-synthase deficiency. Am J Hum Genet 37:1:1-31, 1985.
  90. Mushett CW, Emerson G. Arteriosclerosis in pyridoxine-deficient monkeys and dogs. Fed Proc 4:526-7, 1956.
  91. Ness A, Khaw K, Bingham S, Day NE. Vitamin C status and serum lipids. Eur J Clin Nutr 50; 11:724-9, 1996.
  92. Novelli GP et al. Vitamin E protects human skeletal muscle from damage during surgical ischemia-reperfusion. Am J Surg March 173:206-9, 1997.
  93. Nyyssonen K et al. Vitamin C deficiency and risk of myocardial infarction: prospective population study of men from Eastern Finland. BMJ 314:634-8, 1997.
  94. Ohvall M et al. Gamma, but not alpha tocopherol levels in serum are reduced in coronary heart disease patients. J Int Med 239:111-17, 1996.
  95. Olszewski AJ et al. Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis. Atherosclerosis 75:1:1-6, 1989.
  96. Oster O et al. The serum selenium concentration of patients with acute myocardial infarction. Ann Clin Res 18;1:36-42, 1986.
  97. Pories WJ, Henzel JH, Hennessen JA. Proc U of Missouri First Annual Conference on Trace Substances in the Environment and Health, 1967. 1968:114.
  98. Porkkala-Sarataho E, Nyyssonen K , Salonen JT. Increased oxidation resistance of atherogenic plasma lipoproteins at high vitamin E levels in non-vitamin e supplemented men. Atherosclerosis 124;1:83-94, 1996.
  99. Princen H, van Poppel G, Vogelezang C, et al. Supplementation with vitamin E but not beta carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro: Effect of cigarette smoking. Arter Throm 12:554-62, 1992.
  100. Princen HM, van Duyvenvoorde W, Buytenhek R, et al. Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women. Arterioscler Thromb Vasc Biol 15:325-33, 1995.
  101. Ramirez J, Flowers NC. Leukocyte ascorbic acid and its relationship to coronary artery disease in man. Am J Clin Nutr 3:10:2079-87, 1980.
  102. Rath M, Pauling L. Solution to the puzzle of human cardiovascular disease: its primary cause is ascorbate deficiency leading to the deposition of lipoprotein a and fibrinogen/fibrin in the vascular wall. J Orthomol Med 6:3-4:125-34, 1991.
  103. Rath M, Pauling L. A unified theory of human cardiovascular disease leading the way to the abolition of this disease as a cause for human mortality. J Orthomol Med 7:1:5-15, 1992.
  104. Regnström J, Nilsson J, Moldeus P, et al. Inverse relation between the concentration of low-density- lipoprotein vitamin E and severity of coronary artery disease. Am J Clin Nutr 63:377-85, 1996.
  105. Renaud S, de Lorgeril M, Delaye J, et al. Cretan Mediterranean dietfor prevention of coronary heart disease. Am J Clin Nutr 61suppl:1360S-7S, 1995.
  106. Riemersma RA, Wood DA, MacIntyre CCH, et al. Risk of angina pectoris and plasma concentrations of vitamins A, C and E and carotene. Lancet 337:1-5, 1991.
  107. Rimm EB, Stampfer MJ, Ascherio A, et al. Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 32820:1450-6, 1993.
  108. Rinehart JF, Greenberg LD. Vitamin B6 deficiency in the Rhesus monkey. Am J Clin Nutr 4:318-25, 1956; Rinehart JF, Greenberg LD. Arteriosclerotic lesions in pyridoxine deficient monkeys. Am J Pathol 25:481-96, 1949.
  109. Rinehart JF, Greenberg LD. Pathogenesis of experimental arteriosclerosis in pyridoxine deficiency with notes on similarities to human arteriosclerosis. Arch Pathol 51:12-29, 1951.
  110. Rhinehart JF, Greenberg LD. Vitamin B6 deficiency in the rhesus monkey, with particular reference to the occurrence of atherosclerosis, dental caries and hepatic cirrhosis. Am J Clin Nutr 4:318, 1956.
  111. Sahyoun NR et al. Carotenoids, vitamins C and E, and mortality in an elderly population. Am J Epidemiol 144:5:501-11, 1996.
  112. Salonen JT et al. Association between cardiovascular death and myocardial infarction and serum selenium in a matched-pair longitudinal study. Lancet ii:175-9, 1982.
  113. Salonen JT et al. Interactions of serum copper, selenium, and low density lipoprotein cholesterol in atherogenesis. Br Med J 302:756-60, 1991.
  114. Serfontein WJ, Ubbink JB, De Villiers LS, et al. Plasma pyridoxal-5-phosphate level as risk index for coronary artery disease. Atherosclerosis 55:3:357-61, 1985.
  115. Shah DR et al. Effect of oral zinc sulphate on serum lipids and lipoproteins in human subjects. Indian J Physiol Pharmacol 32;1:47-50, 1988.
  116. Simon E et al. Plasma and erythrocyte vitamin E content in asymptomatic hypercholesterolemic subjects. Clin Chem 43:2:285-9, 1997.
  117. Simons LA, Von Konigsmark M, Balasubramaniam S. What dose of vitamin E is required to reduce susceptibility of LDL to oxidation? Aust N Z J Med 26;4:496-503, 1996.
  118. Singh R, Niaz M, Bishnol J, et al. Diet, antioxidant vitamins, oxidative stress, and risk of coronary artery disease. Acta Cardiol 49:5:453-67, 1994.
  119. Singh RB, Ghosh S, Niaz MA, et al. Dietary intake, plasma levels of antioxidant vitamins and oxidative stress in relation to coronary artery disease in elderly subjects. Am J Cardiol 76:1233-8, 1995.
  120. Singal PK, Dhillon KS, Beamish RE, Dhalla NS. Protective action of zinc against catecholamine-induced myocardial changes. Electrocardiographic and ultrastructural studies. Lab Invest 44:426, 1981.
  121. Singal PK, Kapur N, Dhillon KS et al. Role of free radicals in catecholamine induced cardiomyopathy. Can J Physiol Pharmacol 60:1390, 1982.
  122. Sklodowska M, Wasowicz W, Gromnadzinska J, et al. Selenium and vitamin E concentrations in plasma and erythrocytes of angina pectoris patients. Trace Elem Med 8:113-17, 1991.
  123. Stampfer M, Hennekens C, Manson J, et al. Vitamin E consumption and the risk of coronary heart disease in women. N Engl J Med 328:1444-9, 1993.
  124. Stead NW et al. Selenium Se balance in the dependent elderly. Am J Clin Nutr 39:677, 1984.
  125. Steiner M. Influence of vitamin E on platelet function in humans. J Am Coll Nutr 10;5:466-73, 1991.
  126. Steiner M, Glantz M, Lekos A. Vitamin E plus aspirin compared with aspirin alone in patients with transient ischemic attacks. Am J Clin Nutr 62;suppl:1381S-4S, 1995.
  127. Stephens NG, Parsons A, Schofield PM, et al. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study CHAOS. Lancet 347:781-6, 1996.
  128. Stone WL et al. Effects of dietary selenium and vitamin E on plasma lipoprotein cholesterol levels in male rats. Ann Nutr Metab 30:94-103, 1986.
  129. Street DA et al. Serum antioxidants and myocardial infarction: Are low levels of carotenoids and alpha-tocopherol risk factors for myocardial infarction? Circulation 90;3:1154-61, 1994.
  130. Suadicani P, Hein H, Gyntelberg F. Serum selenium concentration and risk of ischaemic heart disease in an prospective cohort study of 3000 males. Atherosclerosis 96:33-42, 1992.
  131. Subbarao K et al. Pyridoxal 5'-phosphate - a new physiological inhibitor of blood coagulation and platelet function. Biochem Pharmacol 28:531-4, 1979.
  132. Suzukawa M, Ishikawa T, Yoshida H, Tokorozawa N. Effect of in-vivo supplementation with low-dose vitamin E on susceptibility of low-density lipoprotein and high-density lipoprotein to oxidative modification. J Am Coll Nutr 14:1:46-52, 1995.
  133. Takamatsu S, Takamatsu M, Satoh K, et al. Effects on health of dietary supplementation with 100 mg d-alpha tocopheryl acetate, daily for 6 years. J Int Med Res 23:342-57, 1995.
  134. Tomoda H, Yoshitake M, Morimoto K, Aoki N, et al. Possible prevention of postangioplasty restenosis by ascorbic acid. Am J Cardiology 78;11:1284-6, 1996.
  135. Toohey L et al. Plasma ascorbic acid concentrations are related to cardiovascular risk factors in African-Americans. J Nutr 126:121-8, 1996.
  136. Torun M et al. Serum levels of vitamin E in relation to cardiovascular diseases. J Clin Pharm Therap 20:335-40, 1995.
  137. Ubbink JB, Vermaak WJH, van der Merwe A, Becker PJ. Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr 57:47-53, 1993.
  138. Urberg M et al. Hypocholesterolemic effect of nicotinic acid and chromium supplementation. J Fam Pract 27;6:603-6, 1988.
  139. Vallance BD, Hume R, Weyers E. Reassessment of changes in leucocyte and serum ascorbic acid after acute myocardial infarction. Br Heart J 40;1:64-8, 1978.
  140. Verhoef P, Stampfer MJ, Buring JE, et al. Homocysteine metabolism and risk of myocardial infarction: relation with vitamin B6, B12, and folate. Am J Epidemiol 143:9:845-59, 1996.
  141. Verlangieri AJ, Bush MJ. Effects of d-a-tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr 11;2:131-8, 1992.
  142. Vermaak WJH et al. Vitamin B6 and coronary heart disease. Epidemiological observations and case studies. Atherosclerosis 63:235, 1987.
  143. Vijaya I et al. Trace metal analysis in the aorta with and without atherosclerotic lesions. Trace Elem Electrolytes 12;4:200-2, 1995.
  144. Vijayammal PL, Kurup PA. Pyridoxine and atherosclerosis: Role of pyridoxine in the metabolism of lipids and glycosaminoglycans in rats fed normal and high fat, high cholesterol diets containing 16% casein. Austral J Biol Sci 31:1:7-20, 1978.
  145. Virtamo J et al. Serum selenium and the risk of coronary heart disease and stroke. Am J Epidemiol 122:276-82, 1985.
  146. Willis GC, Light AW, Gow WS. Serial arteriography in atherosclerosis. Can Med Assoc J 71:562-8, 1954.
  147. Willis GC, Fishman S. Ascorbic acid content of human arterial tissue. Can Med Assoc J 72:500-3, 1955.
  148. Woodside J et al. the effects of vitamin supplementation on cardiovascular risk. J Inherit Metabol Dis 19:Suppl 1:26/P51, 1996.
  149. Yau TM, Weisel RD, Mickle DA, et al. Vitamin E for coronary bypass operations. A prospective, double-blind, randomized trial. J Thorac Cardiovasc Surg 108;2:302-10, 1994.

 

 

Kræft og kosttilskud - videnskabelige referencer

  1. Albanes D, Heinonen OP, Huttunen JK, et al. Effects of a-tocopherol and b-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study. Am J Clin Nutr 62; suppl:1427S-30S, 1995.
  2. Ambrosone C, Marshal lJ, Vena J, et al. Interaction of family history of breast cancer and dietary antioxidants with breast cancer risk. Cancer Causes 6; 5:407-15, 1995.
  3. Bain C, Green A, Sisking V, et al. Diet and melanoma: an exploratory case-control study. Ann Epidemiol 3:235-8, 1993.
  4. Barone J, Taioli E, Hebert J, et al. Vitamin supplement use and risk for oral and esophageal cancer. Nutr Cancer 18:31-41, 1992.
  5. Bond GG et al. Dietary vitamin A and lung cancer: Results of a case-control study among chemical workers. Nutr Cancer 9:109-21, 1987.
  6. Bostick RM, Potter JD, McKenzie DR, et al. Reduced risk of colon cancer with high intake of vitamin E: The Iowa Women's Health Study. Cancer Res 53:4230-7, 1993.
  7. Bruce WR, Dion PW. Studies relating to a fecal mutagen. Am J Clin Nutr 33:2511-12, 1980.
  8. Bruemmer B et al. Nutrient intake in relation to bladder cancer among middle-aged men and women. Am J Epidemiol 144; 5:485-95, 1996.
  9. Buiatti E et al. A case-control study of gastric cancer and diet in Italy: Association with nutrients. Int J Cancer 45:899-901, 1990.
  10. Bukin YV, Draudin-Krylenko VA, Orlow EN, et al. Effect of prolonged b-carotene or DL-a-tocopheryl acetate supplementation on ornithine decarboxylase activity in human atrophic stomach mucosa. Cancer Epidemiol Biomark Prevent 4:865-70, 1995.
  11. Chajes V, Lhuillery C, Sattler W, et al. Alpha-tocopherol and hydroperoxide content in breast adipose tissue from patients with breast tumors. Int J Cancer 67:170-5, 1996.
  12. Chen J, Geissler C, Parpia B, et al. Antioxidant status and cancer mortality in China. Int J Epidemiol 21:625-35, 1992.
  13. Comstock GW et al. Prediagnostic serum levels of carotenoids and vitamin E as related to subsequent cancer in Washington County, Maryland. Am J Clin Nutr 53:260S-4S, 1991.
  14. Cornee J, Pobel D, Riboli E, et al. A Case-control study of gastric cancer and nutritional factors in Marseille, France. Eur J Epidemiol 11: 55-65, 1995.
  15. Dasgupta J, Sanyal U, Das S. Vitamin E - its status and role in leukemia and lymphoma. Neoplasma 40:235-40, 1993.
  16. De Vries N, Snow GB. Relationships of vitamins A and E and beta-carotene serum levels to head and neck cancer patients with and without second primary tumours. Eur Arch Otorhinolaryngol 247:368-70, 1990.
  17. Eichholzer M, Stahelin HB, Gey KF, et al. Prediction of male cancer mortality by plasma levels of interacting vitamins: 17-year follow-up of the prospective Basal study. Int J Cancer 66:145-50, 1996.
  18. Esteve J, Riboli E, Pequingnot G, Terracine B et al. Diet and cancers of the larynx and hypopharynx: the IARC multi-center study in southwestern Europe. Cancer Causes Control 7:240-52, 1996.
  19. Ferraroni M, La Vecchi C, Davanzo B, et al. Selected micronutrient intake and the risk of colorectal cancer. Br J Cancer 70; 6:1150-5, 1994.
  20. Faber M et al. Lipid peroxidation products, and vitamin and trace element status in patients with cancer before and after chemotherapy, including adriamycin: A preliminary study. Biol Trace Elem Res 47:117-24, 1995.
  21. Fontham ETH et al. Dietary vitamins A and C and lung cancer risk in Louisiana. Cancer 62:2267-73, 1988.
  22. González CA, Riboli E, Badosa J, et al. Nutritional factors and gastric cancer in Spain. Am J Epidemiol 139:466-73, 1994.
  23. Graf N et al. Retinoids in the treatment of acute promyelocytic leukemia: Review of the literature. Klin Pediatr 207:43-7, 1995.
  24. Graham S et al. Dietary factors in the epidemiology of cancer of the larynx. Am J Epidemiol 1136:675-80, 1981.
  25. Gridley G, McLaughlin JK, Block G, et al. Vitamin supplement use and reduced risk of oral and pharyngeal cancer. Am J Epidemiol 135; 10:1083-92, 1992.
  26. Guo W et al. Correlations of dietary intake and blood nutrient levels with oesphageal cancer mortality in China. Nutr Cancer 13:121-7, 1990.
  27. Hasson LE, Nyren O, Bergostrom R, et al. Nutrients and gastric cancer risk: A population-based case-controlled study in Sweden. Int J Cancer 57:638-44, 1994.
  28. Hertog MGL, Feskens EJM, Hollman PCH, et al. Dietary flavonoids and cancer risk in the Zutphen Elderly Study. Nutr Cancer 22:175-84, 1994.
  29. Howe GR, Benito E, Castelleto R, et al. Dietary intake of fiber and decreased risk of cancers of the colon and rectum: evidence from the combined analysis of 13 case-control studies. J Natl Cancer Inst 84(24):1887-96, 1992.
  30. Hsing A et al. Serologic precursors of cancer: Retinol, carotenoids, tocopherol and risk of prostate cancer. J Natl Cancer Inst 82:941-6, 1990.
  31. Jacobson EL, Jacobson MK. A biomarker for the assessment of niacin nutriture as a potential preventive factor in carcinogenesis. J Intern Med 233:59-62, 1993.
  32. Jacobson EL. Niacin deficiency and cancer in women. J Am Coll Nutr 12; 4:412-16, 1993.
  33. Johnson JE, Ringsdorf WM Jr, Cheraskin E. Relationship of vitamin A and oral leukoplakia. Arch Dermatol 88;5:607-12, 1963.
  34. Kinsella JE et al. Metabolism of trans fatty acids with emphasis on the effects of trans, trans-octadecadienoate on lipid composition, essential fatty acid, and prostaglandins: An overview. Am J Clin Nutr 34:2307, 1981).
  35. Kirkpatrick CS, White E, Lee JAH. Case-control study of malignant melanoma in Washington State. II. Diet, alcohol, and obesity. Am JEpidemiol 139:869-80, 1994.
  36. Knekt P. Serum alpha tocopherol and the risk of cancer. Helsinki, Publications of the Social Insurance Institution, Finland, ML, Vol 83, 1983.
  37. Knekt P et al. Serum vitamin E and risk of cancer among Finnish men during a 10-year follow-up. Am J Epidemiol 127; 1:28-41, 1988.
  38. Knekt P et al. Vitamin E and cancer prevention. Am J Clin Nutr 53:283S-6S, 1991.
  39. Ko W-F, Helzlsouer JK, Morris, et al. The association between antioxidant micronutrients and anatomic site-specific incidence of colon cancer. Abstract. J Am Coll Nutr 12:586, 1993.
  40. Koch HF. Effect of retinoids on precancerous lesions of the oral cavity, in CE Orfanos, O Braun-Falco, EM Farber, et al, Eds. Retinoids: Advances in Basic Research and Therapy. Berlin, Springer, 1981:307-12.
  41. Kolonel LN et al. Association of diet and place of birth with stomach cancer incidence in Hawaii Japanese and Caucasians. Am J Clin Nutr 34; 11:2478-85, 1981.
  42. Kune GA et al. Serum levels of b-carotene, vitamin A and zinc in male lung cancer cases and controls. Nutr Cancer 12:169-76, 1989.
  43. Lane, William & Comac, Linda: Sharks still donīt get Cancer; Avery Publ. Group Inc.,New York, N.Y., 1996.
  44. Langer, Robert & Lee, A; Shark Cartilage contains Inhibitors of Tumor Angiogenesis; Science; vol 221, Sep. 9., 1983.
  45. LeGardeur BY et al. A case-control study of serum vitamins A, E, and C in lung cancer patients. Nutr Cancer 14:133-40, 1990.
  46. Lippman SM, Meyskens ML Jr. Vitamin A derivatives in the prevention and treatment of human cancer. J Am Coll Nutr 7; 4:269-84, 1988.
  47. Losonczy KG, Harris TB, Havlik RJ. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly. Am J Clin Nutr 64:190-6, 1996.
  48. Mayne ST, Janerich DT, Greenwald P, et al. Dietary beta-carotene and lung cancer risk in U.S. nonsmokers. J Natl Cancer Inst 86:33-8, 1994.
  49. Menkes MS et al. Serum beta-carotene, vitamins A and E and the risk of lung cancer. J Am Coll Nutr 6:425, 1987; Menkes MS et al. Serum beta-carotene, vitamins A and E, selenium and the risk of lung cancer. N Engl J Med 315:1250, 1986.
  50. Michalek AM et al. Vitamin A and tumor recurrence in bladder cancer. Cancer 9:143-6, 1987.
  51. Monoharan S, Nagini S. Lipid peroxidation and antioxidant status in oral cancer patients. Med Sci Res 22:291-2, 1994.
  52. Negri E, LaVecchia C, Franceschi S, et al. Intake of selected micronutrients and the risk of breast cancer. Int J Cancer 65:140-4, 1996.
  53. Nomura A et al. Dietary factors in cancer of the lower urinary tract. Int J Cancer 48:199-205, 1991.
  54. Noto V et al. Effects of sodium ascorbate vitamin C and 2-methyl-1,4-naphthoquinone vitamin K3 treatment on human tumor cell growth in vitro. I. Synergism of combined vitamin C and K3 action. Cancer 63:901-6, 1989.
  55. Ocke M, Bueno-deo-Mesquita H, Feskens E et al. Repeated measurements of vegetables, fruits, b-carotene, and vitamins C and E in relation to lung cancer. Am J Epidemiol 145; 4:358-65, 1997.
  56. Orr JW Jr et al. Nutritional status of patients with untreated cervical cancer. II. Vitamin assessment. Am J Obstet Gynecol 1515:632-5, 1985.
  57. Pascoe GA, Reed DJ. Vitamin E protection against chemical-induced cell injury. II. Evidence for a threshold effect of cellular a-tocopherol in prevention of adriamycin toxicity. Arch Biochem Biophys 256:159-66, 1987.
  58. Prasad KN et al. Vitamin E increases the growth inhibitory and differentiating effects of tumor therapeutic agents on neuroblastoma and glioma cells in culture. Proc Soc Exp Biol Med 164; 2:158-63, 1980.
  59. Palan PR et al. Plasma levels of antioxidant beta-carotene and alpha-tocopherol in uterine cervix dysplasias and cancer. Nutr Cancer 15:13-20, 1991.
  60. Palan P, Mikhail M, Goldberg G, et al. Plasmalevels of beta-carotene, lycopene canthanxanthin, retinol, and alpha-tocopherol and tau-tocopherol in cervical intraepithelial neoplasia and cancer. Clin Cancer 2;1:181-5, 1996.
  61. Ramaswamy P, Natarajan R. Vitamin B6 status in patients with cancer of the uterine cervix. Nutr Cancer 6:176-80, 1984.
  62. Reichman M et al. Serum vitamin A and subsequent development of prostate cancer in the first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. Cancer Res 50:2311-15, 1990.
  63. Reddy BS. Chemoprevention of colon cancer by dietary fatty acids. Cancer Metastasis Rev 13(3-4):285-302, 1994.
  64. Risch HA, Jain M, Marrett LD, Howe GR. Dietary fat intake and risk of epithelial ovarian cancer. Am J Epidemiol 139(11):S37, 1994.
  65. Rock CL, Saxe GA, Ruffin MT, et al. Carotenoids, vitamin A and estrogen receptor status in breast cancer. Nutr Cancer 25:281-96, 1996.
  66. Romney SL et al. Plasma vitamin C and uterine cervical dysplasia. Am J Obstet Gynecol 151:976-80, 1985.
  67. Shibata A, Paganini-Hill A, Ross RK, Henderson BE. Intake of vegetables, fruits, beta-carotene, vitamin C and vitamin supplements and cancer incidence among the elderly: a prospective study. Br J Cancer 66; 4:673-9, 1992.
  68. Singh RB, Niaz MA, Ghosh S, et al. Dietary intake and plasma levels of antioxidant vitamins in health and disease: a hospital-based case-control study. J Nutr Environ Med 5:235-42, 1995.
  69. Spigelman AD, Uff CR, Phillips RK. Vitamin C levels in patients with familial adenomatous polyposis. Br J Surg 77; 5:508-9, 1990.
  70. Stähelin HB et al. Cancer, vitamins, and plasma lipids: Prospective Basel study. J Natl Cancer Inst 73; 6:1463-8, 1984.
  71. Stich HF, Hornby AP, Matthew B, et al. Response of oral leukoplakias to the administration of vitamin A. Cancer Lett 40:93-101, 1988.
  72. Stich H et al. Remission of oral precancerous lesions of tobacco/areca nut chewers following administration of beta carotene or vitamin A, and maintenance of the protective effect. Cancer Det 15:93-8, 1991.
  73. Stich HF, Mathew B, Sankaranarayanan R, Krishnan Nair M. Remission of precancerous lesions in the oral cavity of tobacco chewers and maintenance of the protective effect of b-carotene or vitamin A. Am J Clin Nutr 53:298S-304S, 1991.
  74. Stoll BA. Can supplementary dietary fiber suppress breast cancer growth? Br J Cancer 73:557-9, 1996.
  75. Stryker W et al. Diet, plasma levels of beta carotene and alpha tocopherol, and risk of malignant melanoma. Am J Epidemiol 13:597-611, 1990.
  76. Tseng M, Murray SC, Kupper LL, Sandler RS. Micronutrients and the risk of colorectal adenomas. Am J Epidemiol 144; 11:1005-14, 1996.
  77. Van T, Veer P et al. Dietary fiber, beta-carotene and breast cancer: Results from a case-control study. Int J Cancer 4:825-8, 1990.
  78. Verreault R et al. A case-control study of diet and invasive cervical cancer. Int J Cancer 43:1050-4, 1989.
  79. Vlajinac HD et al. Diet and prostate cancer: A case-control study. Eur J Cancer 33; 1:101-7, 1997.
  80. Wadleigh RG, Redman RS, Graham ML, et al. Vitamin E in the treatment of chemotherapy-induced mucositis. Am J Med 92; 5:481-4, 1992.
  81. Walker, Morton; Why Shark Cartillage should Succeed against Cancer & other Pathologies; Townsend Letter For Doctors; 100, p. 847; 1991.
  82. Wald NJ et al. Plasma retinol, beta-carotene and vitamin E levels in relation to the future risk of breast cancer. Br JCancer 49:321-4, 1984.
  83. Willett WC. Micronutrients and cancer risk. Am J Clin Nutr 59(suppl):1162S-5S, 1994.
  84. Wood L. Possible prevention of adriamycin-induced alopecia by tocopherol. Letter. N Engl J Med 312; 16:1060, 1985.
  85. Zheng W, Sellers TA, Doyle TJ, et al. Retinol, antioxidant vitamins, and cancer of the upper digestive tract in a prospective cohort study of postmenopausal women. Am J Epidemiol 142:955-60, 1995.
  86. Zhenrong Z, Parvianen M, Mannisto S et al. Vitamin E concentration in breast adipose tissue of breast cancer patients. Cancer Causes Control 7:591-95, 1996.

 

Allergi og kosttilskud - videnskabelige referencer

  1. Ahmad K, Jahan K. Studies on the preventive and curative action of ascorbic acid on the neurological toxicity of monosodium glutamate. Food Nutr Bull 7(1):51-3, 1985.
  2. Amellal M, Bronner C, Briancon F, et al. Inhibition of mast cell histamine release by flavonoids and bioflavonoids. Planta Medica 1985:16-20.
  3. Bekier E, Maslinski CZ. Antihistaminic action of nicotinamide. Agents Actions 4(3):196, 1974.
  4. Bouhuys A. Colds and antihistaminic effects of vitamin C. N Engl J Med 290(11):633, 1974.
  5. Caldwell EJ et al. Histamine and ascorbic acid: A survey of women in labor at term and significantly before term. Int J Vitam Nutr Res 58(3):319-25, 1988.
  6. Chatterjee IB et al. Effect of ascorbic acid on histamine metabolism in scorbutic guinea-pigs. J Physiol 251:271-9, 1975.
  7. Clark W, Mackay E, Effect of flavonoid substances on histamine toxicity, anaphylactic shock and histamine-enhanced capillary permeability to dry. J Allergy 21:133-47, 1950.
  8. Clemetson C, Alan B, et al. Histamine and ascorbic acid in human blood. J Nutr 110(4):662-8, 1980.
  9. Folkers K et al. Biochemical evidence for a deficiency of vitamin B6 in subjects reacting to monosodium-L-glutamate by the Chinese restaurant syndrome. Biochem Biophys Res Commun 100:972-7, 1981.
  10. Johan S Alm, Jackie Swartz, Gunnar Lilja, Annika Scheynius, Göran Pershagen: Atopy in children of families with an antroposophic lifestyle, Lancet; 353: 1485-88.
  11. Moussatche H, Prouvost-Danon A. Inhibition by nicotinamide and nicotinic acid of histamine release in the anaphylactic reaction in vitro. Influence of some metabolites. An Acad Brasileira de Ciencias 33:173-78, 1961.
  12. Shasheen SO, Aaby P, Hall AJ et al. Measles and atopy in Guinea-Bissau. Lancet 1996; 347: pp 1792-96.
  13. Simon SW. Vitamin B12 therapy in allergy and chronic dermatoses. J Allergy 2:183-5, 1951.
  14. Johnston CS, Retrum KR, Srilakshmi JC. Antihistamine effects and complications of supplemental vitamin C. J Am Diet Assoc 92(8):988- 9, 1992.
  15. Nandi BK et al. Effect of ascorbic acid on detoxification of histamine under stress conditions. Biochem Pharmacol 23(3):643-7, 1974.
  16. Pavlovic S, Fraser R. Effects of different levels of vitamin C on the vitamin C concentration of guinea pigs plasma and the effect of vitamin C intake on anaphylaxis. Med Interne 26(3):235-44, 1988.
  17. Feigen GA et al. Enhancement of antibody production and protection against systemic anaphylaxis by large doses of vitamin C. Res Commun Chem Pathol Pharmacol 38(2):313-33, 1982.
  18. Bucca C et al. Effect of vitamin C on histamine bronchial responsiveness of patients with allergic rhinitis. Ann Allergy 65:311-4, 1990.
  19. Ruskin SL. Sodium ascorbate in the treatment of allergic disturbances. The role of adrenal cortical hormone-sodium-vitamin C. Am J Dig Dis 14:302-6, 1947.
  20. Brown EA, Ruskin S. The use of cevitaminic acid in the symptomatic and coseasonal treatment of pollinosis. Ann Allergy 7:65-70, 1949.
  21. Kamimura M. Antiinflammatory activity of vitamin E. J Vitaminol 18(4):204-9, 1972.
  22. Utz G, Hauck AM. Oral application of calcium and vitamin D2 in allergic bronchial asthma. MMW 118(43):1395-8, 1976.
  23. Fantidis P, Ruiz Cacho J, Marin M, et al. Intracellular (polymorphonuclear) magnesium content in patients with bronchial asthma between attacks. J R Soc Med 88(8):441-5, 1995.
  24. Galland L. Magnesium and immune function: an overview. Magnesium 7(5-6):290-9, 1988.
  25. Durlach J. Magnesium and allergy: experimental and clinical relationships between magnesium and hypersensitivity. Rev Fr Allergol 15:133-46, 1975.
  26. Rogers SA. Zinc deficiency as model for developing chemical sensitivity. Int Clin Nutr Rev 10(1):253-9, 1990.
  27. Marone G et al. Physiological concentrations of zinc inhibit the release of histamine from human basophils and lung mast cells. Agents Actions 18(1-2):103-6, 1986.
  28. Middleton E Jr et al. The effects of citrus flavonoids on human basophil and neutrophil function. Planta Medica 53:325-8, 1987.
  29. Gäbor M. Anti-inflammatory and anti-allergic properties of flavonoids. Prog Clin Biol Res 213:471-80, 1986.
  30. Middleton E Jr. Effect of flavonoids on basophil histamine release and other secretory systems. Prog Clin Biol Res 213:493-506, 1986.
  31. Schoenkerman B, Justice R. Treatment of allergic disease with a combination of antihistamine and flavonoid. Ann Allergy 10:138-41, 1952.
  32. Wendt P et al. The use of flavonoids as inhibitors of histidine decarboxylase in gastric diseases: Experimental and clinical studies. Naunyn Schmiedebergs Arch Pharmacol (Suppl) 313:238, 1980.
  33. Ogasawara H, Middleton E Jr. Effect of selected flavonoids on histamine release (HR) and hydrogen peroxide (H2O2) generation by human leukocytes. J Allergy Clin Immunol 75:184, 1985.
  34. Middleton E Jr, Drzewiecki G. Flavonoid inhibition of human basophil histamine release stimulated by various agents. Biochem Pharmacol 33(21):3333, 1984.
  35. Pearce FL et al. Mucosal mast cells III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells. J Allergy Clin Immunol 73:819- 23, 1984.
  36. Pantethine: possible treatment for formaldehyde sensitivity. Ecological Formulas, 1061-B Shary Circle, Concord, CA 94518, 1986.
  37. Wei W, Kranz KB. A synergism of antigen challenge and severe magnesium deficiency on blood and urinary histamine levels in rats. J Am Coll Nutr 9(6):616-22, 1990.
  38. Yoshimoto T et al. Flavonoids: Potent inhibitors of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun 116:612-18, 1983.

 

Gigt/rheumatisme og kosttilskud - videnskabelige referencer

  1. Aeseth J et al. Trace elements in serum and urine of patients with rheumatoid arthritis. Scand J Rheumatol 7:237-40, 1978.
  2. Alter HJ, Zvaifler MJ, Rath CE. Interrelationship of Rheumatoid Arthritis, Folic Acid and Aspirin. Blood 38: 405-16, 1971.
  3. Andrews FJ et al. Effect of nutritional iron deficiency on acute and chronic inflammation. Ann Rheum Dis 46(11): 859-65, 1987.
  4. Balogh Z et al. Plasma Zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis. Ann Rheum Dis 39(4): 329-32, 1980.
  5. Banford JC et al. Serum Copper and Erythrocyte Superoxide Dismutase in Rheumatoid Arthritis. Ann Rheum Dis 41(5): 458-62, 1982.
  6. Barton-Wright EC, Elliott WA. The pantothenic acid metabolism of rheumatoid arthritis. Lancet ii:862-3, 1963.
  7. Belch JJ, Ansell D, Madhok R, et al. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. Ann Rheum Dis 47(2): 96-104, 1988.
  8. Blake DR et al. The importance of iron in rheumatoid disease. Lancet ii: 1142-4, 1981.
  9. Bland, J. Copper salicylates and complexes in molecular medicine. Int Clin Nutr Rev 4(3): 130-4, 1984.
  10. Blankenhorn G. Vitamin E: Clinical research from Europe. Nutr Dietary Consult June, 1988.
  11. Bruce A et al. The effect of selenium and vitamin E on glutathione peroxidase levels and subjective symptoms in patients with arthrosis and rheumatoid arthritis, in Proc N Z Workshop on Trace Elements in N Z. Dunedin, U. of Otago, 1981: 92.
  12. Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol 30(5): 370-2, 1991.
  13. Caughey GE, Mantzioris, Gibson RA, et al. The effect of human necrosis factor and interleukin 1b production of diets enriched in n-3 fatty acids from vegetable or fish oil. Am J Clin Nutr 63: 116-22, 1996.
  14. Charrot A. Silicon supplementation, Maroc Med 377: 32, 1952.
  15. Chung MH et al. Degradation of Articular Cartilage by Copper and Hydrogen Peroxide. Agents Actions 15: 328-35, 1984.
  16. Cleland LG et al. Clinical and biochemical effects of dietary fish oil supplements in rheumatoid arthritis. J Rheumatol 15(10): 1471-5, 1988.
  17. Cohen A and Goldman J. Bromelain Therapy in Rheumatoid Arthritis. Penn Med J 67: 27-30, 1964.
  18. Comstock GW et al. Serum concentrations of alpha-tocopherol, beta-carotene, and retinol preceding the diagnosis of rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 56: 323-5, 1997.
  19. Conforti A, Franco L, Menegale G, et al. Serum copper and ceruloplasmin levels in rheumatoid arthritis and degenerative joint disease and their pharmacological implications. Pharmacol Res Commun 15(9): 859-67, 1983.
  20. Cotzias GC et al. Slow turnover of manganese in active rheumatoid arthritis and acceleration by prednisone. J Clin Invest 47:992, 1968.
  21. Cunnane SC et al. Alpha-Linolenic Acid in Humans: Direct Functional Role or Dietary Precursor. Nutrition 7: 437-9, 1991.
  22. Dabbagh AJ. Trenam CW, Morris CJ, Blake DR. Iron in joint inflammation. Ann Rheum Dis 52:67-73, 1993.
  23. Das UN. Interactions (s) between essential fatty acids, eicosanoids, cytokines, growth factors and free radicals: relevance to new therapeutic strategies in rheumatoid arthritis and other collagen vascular diseases. Prostaglandins Leukot Essent Fatty Acids 44(4):201-10, 1991.
  24. Davidson A et al. Red cell ferritin content: A re-evaluation of indices for iron deficiency in the anaemia of rheumatoid arthritis. Br Med J 289: 648-50, 1984.
  25. Deller DJ et al. Folic acid deficiency in rheumatoid arthritis. Relation of levels of serum folic acid activities to treatment with phenylbutazone. Br Med J i: 765-7, 1966.
  26. DiSilvestro RA, Marten J, Skehan M. Effects of copper supplementation on ceruloplasmin and copper-zinc superoxide dismutase in free-living rheumatoid arthritis patients. J Am Coll Nutr 11(2):177-80, 1992.
  27. Dijkmans BA et al. Serum aluminium concentrations in patients with rheumatoid arthritis. Scand J Rheumatol 16; 5:361-4, 1987.
  28. Ellis JM. Vitamin B6 deficiency and rheumatism. Anabolism Winter 1985.
  29. Fritshe KL et al. Rapid Autoxidation of Fish Oil in Diets without Added Antioxidants. J Nutr 118: 425-6, 1988.
  30. Geusens P, Wouters C, Nijs J, et al. Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. Arthritis Rheum 37(6): 824-9, 1994.
  31. Gough KR et al. Folic acid deficiency in rheumatoid arthritis. Br Med J i: 212-17, 1964.
  32. Grennan DM et al. Serum copper and zinc in rheumatoid arthritis and osteoarthritis. N Z Med J 91(652): 47-50, 1980.
  33. Hangarter W. Copper salicylate in rheumatoid arthritis and rheumatism-like degenerative diseases. Med Welt 31:1625, 1980.
  34. Hansen TM et al. Serum ferritin and the assessment of iron deficiency in rheumatoid arthritis. Scand J Rheumatol 12(4): 353-9, 1983.
  35. Hansen TM, Hansen NE. Serum ferritin as indicator of iron responsive anemia in patients with rheumatoid arthritis. Ann Rheum Dis 45: 569, 1986.
  36. Harats D et al. Fish Oil Ingestion in Smokers and Nonsmokers Enhances Peroxidation of Plasma lipoproteins. Atherosclerosis 90: 127-39, 1991.
  37. Heliovaara M, Knekt P, Aho K, et al. Serum antioxidants and risk of rheumatoid arthritis. Ann Rheum Dis 53: 51-3, 1994.
  38. Honkanen V et al. Vitamins A and E, retinol binding protein and zinc in rheumatoid arthritis. Clin Exp Rheumatol 7: 465-9, 1989.
  39. Honkanen VEA et al. Serum cholesterol and vitamins A and E in juvenile chronic arthritis. Clin Exp Rheumatol 8: 187-91, 1990.
  40. Honkanen VEA et al. Plasma zinc and copper concentrations in rheumatoid arthritis: Influence of dietary factors and disease activity. Am J Clin Nutr 54: 1082-6, 1991.
  41. Hopkins P. Phenylalanine & relief of chronic pain. Anabolism (4)2, 1985.
  42. Horger I. Enzyme Therapy in Multiple Rheumatic Diseases. Therapiewoche 33: 3948-57, 1983.
  43. Horger I, Moro V, Van Schaik W. Zirkulierende Immunkomplexe bei Polyarthritis-patienten. Natur-und Ganzheits -Medizin 1: 177-22,1988 (in German).
  44. Horrobin DF. The importance of gamma-linolenic acid and prostaglandin E 1 in human nutrition and medicine. J Holistic Med 3: 118-39, 1981.
  45. Jacka T et al. Copper salicylate as an anti-inflammatory and analgaesic agent in arthritic rats. Life Sci 32: 1023, 1983.
  46. Jantti J et al. Evening Primrose Oil in Rhaumatoid Arthritis: Changes in Serum Lips and Fatty Acids. Ann Rheum Dis 48: 124-7, 1989.
  47. Kelley DS. Alpha-Linolenic Acid and Immune Response. Nutrition 8: 215-7, 1992.
  48. Kishore V et al. Effect of a nutritional copper deficiency on the development of adjuvant arthritis in the rat, in DD Hemphill, Ed. Trace Substances in Environmental Health XVI. Columbia, MO, U. of Missouri, 1982.
  49. Kremer JM et al. Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis. Lancet i: 184-7, 1985.
  50. Kremer JM, Jubiz W, Michalek A, et al. Fish-oil fatty acid supplementation in active rheumatoid arthritis. A double-blinded, controlled, crossover study. Ann Intern Med 106(4): 497-503, 1987.
  51. Kremer JM et al. Fish-Oil Supplementation in Active Rheumatoid Arthritis: A Double-Blinded Controlled Cross-Over Study. Ann Intern Med 106: 497-502, 1987.
  52. Kremer JM et al. Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects. Arthritis Rheum 33(6): 810-20, 1990.
  53. Kremer JM. Clinical studies of omega-3 fatty acid supplementation in patients who have rheumatoid arthritis. Rheum Dis Clin North Am 17(2): 391-402, 1991.
  54. Kremer JM, Lawrence DA, Petrillo GF, et al. Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs. Arthritis Rheum 38(8):1107-14, 1995.
  55. Kremer JM. Effects of modulation of inflammatory and immune parameters in patients with rheumatic and inflammatory disease receiving dietary supplementation of n-3 and n-6 fatty acids. Lipids 31(suppl): S243-S247, 1996.
  56. Kremer JM, Bigaouette J. Nutrient intake of patients with rheumatoid arthritis is deficient in pyridoxine, zinc, copper, and magnesium. J Rheumatol 23(6): 990-4, 1996.
  57. Kroger H, Penttila I, Alhava E. Low serum vitamin D metabolites in women with rheumatoid arthritis. Scand J Rheumatol 22: 172-7, 1993.
  58. Kunkel SL, Ogawa H, Ward PA, Zurier RB. Suppression of chronic inflammation by evening primrose oil. Prog Lipid Res 20: 885-8, 1982.
  59. Laganiere S, Fernandes G. High peroxidizability of subcellular membrane induced by high fish oil diet is reversed by vitamin E. Clin Res 35: A565, 1987.
  60. Lau CS, Morley KD, Belch JJ. Effects of fish oil supplementation on non-steroidal anti-inflammatory drug requirement in patients with mild rheumatoid arthritis - a double-blind placebo controlled study. Br J Rheumatol 32(11): 982-9, 1993.
  61. Leslie CA et al. Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibility in mice. J Exp Med 162(4): 1336-49, 1985.
  62. Leventhal LJ, Boyce EG, Zurier RB. Treatment of arthritis with gammalinolenic acid. Ann Intern Med 119: 867-73, 1993.
  63. Levine M. New Concepts in the Biology and Biochemistry of Ascorbic Acid. New Eng J Med 314: 892-902, 1986.
  64. Lewis AJ. The Role of Copper in Inflammatory Disorders. Agents Actions: 513-9, 1984.
  65. Mantzioris E et al. Dietary Substitution with Alpha-Linolenic Acid-Rich Vegetable Oil Increases Eicosapentaenoic Acid
  66. Concentrations in Tissues. Am J Clin Nutr 59: 1304-9, 1994.
  67. Mattingly PC et al. Zinc Sulphate in Rheumatoid Arthritis. Ann Rheuma Dis 41: 456-7, 1982.
  68. McAdam P. Chicken cartilage assessed in rheumatoid arthritis. Med Tribune, Nov. 4, 1993: 8.
  69. Modesto C, Castro L. Folinic acid supplementation in patients with juvenile rheumatoid arthritis treated with methotrexate. J Rheumatol 23(2): 403-4, 1996.
  70. Morgan SI, Alarcon GS, Krumdieck CL. Folic acid supplementation during methotrexate therapy: It makes sense. Editorial. J Rheumatol 20(6): 929-30, 1993.
  71. Morgan SL, Baggott JE, Vaughn WH, et al. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis: a double-blind, placebo-controlled trial. Ann Intern Med 121: 833-41, 1994.
  72. Morgan SL, Anderson AM, Hood SM, et al. Nutrient intake patterns, body mass index, and vitamin levels in patients with rheumatoid arthritis. Arthritis Care Res 10(1): 9-17, 1997.
  73. Moss M. Effects of molybdenum on pain and general health: A pilot study. J Nutr Environ Med 5: 55-61, 1995.
  74. Muirden KD, Senator GB. Iron in the synovial membrane in rheumatoid arthritis and other joint diseases. Ann Rheum Dis 27: 38-48, 1968.
  75. Mullen A, Wilson CWM. The metabolism of ascorbic acid in rheumatoid arthritis. Proc Nutr Sci 35: 8A-9A, 1976.
  76. Munthe E, Aaseth J. Treatment of Rheumatoid Arthritis with Selenium and Vitamin E. Scan J of Rheumatol 53 (suppl.): 103, 1984.
  77. Munthe E, Aaseth J, Jellum E. Trace elements and rheumatoid arthritis (RA) - pathogenetic and therapeutic aspects. Acta Pharmacol Toxicol (Copenh) 7: 365-73, 1986.
  78. Mussalo-Rauhamaa H et al. Predictive clinical and laboratory parameters for serum zinc and copper in rheumatoid arthritis. Ann Rheum Dis 47(10): 816-19, 1988.
  79. Naveh Y et al. Zinc metabolism in rheumatoid arthritis: plasma and urinary zinc and relationship to disease activity. J Rheumatol 24(4): 643-6, 1997.
  80. Neligan AR, Salt HB. Sulphur in rheumatoid arthritis. Lancet ii: 209, 1934.
  81. Nettleton JA. Omega-3 Fatty Acids: Comparison of Plant and Seafood Sources in Human Nutrition. J Am Diet Assoc 91: 331-7, 1991.
  82. Newnham RE. Boron beats arthritis. Proc ANZAAS, Australian Academy of Science, Canberra, Australia, 1979.
  83. Newnham RE. Arthritis or skeletal fluorosis and boron. Letter. Int Clin Nutr Rev 11(2): 68-70, 1991.
  84. Newnham RE. The role of boron in human nutrition. J Appl Nutr 46(3): 81-5, 1994.
  85. Niedermeier W. Concentration and chemical state of copper in synovial fluid and blood serum of patients with rheumatoid arthritis. Ann Rheum Dis 24: 544, 1965.
  86. Nielsen G, Faarvang K, Thomsen B, et al. The effects of dietary supplementation with n-3 polyunsaturated acids in patients with rheumatoid arthritis: A randomized double blind trial. Eur J Clin Invest 22: 687-91, 1992.
  87. Okuyama S et al. Copper complexes of non-steroidal antiinflammatory agents: Analgesic activity and possible opioid receptor activation. Agents Actions 21(1-2): 130-44, 1987.
  88. Oldroyd KG, Dawes PT. Clinically significant vitamin C deficiency in rheumatoid arthritis. Br J Rheumatol 24: 362-3, 1985.
  89. Pandley SP et al. Zinc in rheumatoid arthritis. Indian J Med Res 81: 618-20, 1985.
  90. Pasquier C et al. Manganese-Containing Superoxide-Dismutase Deficiency in Polymorphonuclear Leucocytes of Adults with Rheumatoid Arthritis. Inflamm 8: 27-32, 1984.
  91. Peretz A, Nève J, Famaey J. Selenium in rheumatic diseases. Semin Arthritis Rheum 20: 305-16, 1991.
  92. Peretz A, Nève J, Duchateau J, Famaey JP. Adjuvant treatment of recent onset rheumatoid arthritis by selenium supplementation: Preliminary observations. Br J Rheumatol 31: 281-6, 1992.
  93. Peretz A, Nève J, Jeghers O, Pelen F. Zinc distribution in blood components, inflammatory status, and clinical indexes of disease activity during zinc supplementation in inflammatory rheumatic diseases. Am J Clin Nutr 57: 690-4, 1993.
  94. Prudden JF, Balassa LL. The biological activity of bovine cartilage preparations. Semin Arthritis Rheum 3(4): 287-321, 1974.
  95. Pullman-Mooar S, Laposata M, Lem D, et al. Alteration of the cellular fatty acid profile and the production of eicosanoids in human monocytes by gamma-linolenic acid. Arthritis Rheum 33(10): 1526-33, 1990.
  96. Reed A et al. 25-hydroxyvitamin D therapy in children with active juvenile rheumatoid arthritis: Short-term effects on serum osteocalcin levels and bone mineral density. J Pediatr 119(4): 657-60, 1991.
  97. Reddy ACP, Lokesh BR. Dietary unsaturated fatty acids, vitamin E, curcumin and eugenol alter serum and liver lipid peroxidation in rats. Nutr Res 14: 1423-37, 1994.
  98. Rosa GD et al. Regulation of Superoxide Dismutase Activity by Dietary Manganese. J Nutr 110: 795-804, 1980.
  99. Rothman D, DeLuca P, Zurier RB. Botanical lipids: Effects on inflammation, immune responses, and rheumatoid arthritis. Semin Arth Rheum 25(2): 87-96, 1995.
  100. Roubenoff R et al. Abnormal vitamin B6 status in rheumatoid cachexia. Arthritis Rheum 1: 105-9, 1995.
  101. Sahud MA, Cohen RJ. Effect of aspirin ingestion on ascorbic-acid levels in rheumatoid arthritis. Lancet i: 937-8, 1971.
  102. Scadding GK, Ayesh R, Brostoff J, et al. Poor sulphoxidation ability in patients with food sensitivity. Br Med J 297: 105-7, 1988.
  103. Sculti L. Arthritis benefits from shark cartilage therapy. Alt Comp Therap, Oct. 1994: 35-7.
  104. Senator GB, Muirden KD. Concentration of iron in synovial membrane, synovial fluid and serum in rheumatoid arthritis and other joint diseases. Ann Rheum Dis 27: 49-54, 1968.
  105. Senturia BD. Results of Treatment of Chronic Arthritis and Rheumatoid Conditions with Colloidal Sulphur. J Bone Joint Surg 16: 119-25, 1934.
  106. Simkin PA. Oral zinc sulphate in rheumatoid arthritis. Lancet ii: 539-42, 1976.
  107. Simkin PA. Treatment of Rheumatoid Arthritis with Oral Zinc Sulfate. Agents and Actions (suppl.) 8: 587-95, 1981.
  108. Singh RB, Niaz MA, Ghosh S, et al. Dietary intake and plasma levels of antioxidant vitamins in health and disease: a hospital-based case-control study. J Nutr Environ Med 5: 235-42, 1995.
  109. Sklodowska M et al. Vitamin E, thiobarbituric acid reactive substance concentrations and superoxide dismutase activity in the blood of children with juvenile rheumatoid arthritis. Clin Exp Rheumatol 14: 433-9, 1996.
  110. Sorenson JRJ. Copper chelates as possible active forms of anti-arthritic agents. J Med Chem 19: 135, 1976.
  111. Sorenson JRJ, Hangarter W. Treatment of Rheumatoid and Degenerative Diseases with Copper Complexes: A review with Emphasis on Copper-salicylate. Inflammation 2(3): 217-38, 1977.
  112. Sorenson JRJ. Copper complexes: A unique class of anti-arthritic drugs. Prog Med Chem 15: 211, 1978.
  113. Sorenson JRJ. The Anti-inflammatory Activities of Copper Complexes, Metal Ions and Biological Systems. Marcel Dekker, 1982: 77-125.
  114. Svenson KL et al. Reduced zinc in peripheral blood cells from patients with inflammatory connective tissue diseases. Inflammation 9(2): 189-99, 1985.
  115. Tarp U et al. Low selenium level in severe rheumatoid arthritis. Scand J Rheumatol 14: 97, 1985.
  116. Tarp U et al. Selenium Treatment in Rheumatoid Arthritis. Scandinavian J of Rheumatol 14: 364-8, 1985.
  117. Toda S et al. Natural Antioxidants: Antioxidative Compounds Isolated from Rhizome of Curcuma longa L. Chem Pharmacol Bull 33: 1725-8, 1985.
  118. Vreugdenhil G et al. Efficacy and safety of oral iron chelator L1 in anaemic rheumatoid arthritis patients. Letter. Lancet ii: 1398-9, 1989.
  119. Watts DL. The nutritional relationships of copper. J Orthomol Med 4(2): 99-108, 1989.
  120. Wiesel LL et al. The synergistic action of para-amino-benzoic acid and cortisone in the treatment of rheumatoid arthritis. Am J Med Sci 222: 243-8, 1951.
  121. Youssef AA et al. Serum copper: A marker of disease activity in rheumatoid arthritis. J Clin Pathol 36(1): 14-17, 1983.
  122. Zaphiropoulos GC. Rheumatoid Arthritis and the Gut. Br J Rheum 25: 138-40, 1986.
  123. Zielonka E et al. Sulfur and selenium levels in the blood of patients with rheumatoid arthritis and ankylosing spondylitis. Reumatologia 20(3-4): 217-20, 1982.

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